NASDAQ · Financial Statements

Agios Pharmaceuticals, Inc. (AGIO) Financial Statements

$37.00 NASDAQ: AGIO Market Cap $2.21B

Agios Pharmaceuticals, Inc. most recently reported annual revenue of $54.0M, a net loss of $413.0M. See the full income statement, balance sheet, and cash flow statement below, plus valuation and return ratios.

Agios Pharmaceuticals, Inc.: Revenue fell from $70.0M in 2016 to $54.0M in 2025, a change of -22.9% over 9 years; net profit was positive in 2 of 10 reported years; operating margin moved from -287.6% to -873.9%, a shift of -586.3 percentage points; the most recent year shows a net loss of $413.0M.

Income Statement — 10 Years (USD millions)

Metric2016201720182019202020212022202320242025
Revenue$70.0M$43.0M$94.0M$118.0M$0$0$14.0M$27.0M$36.0M$54.0M
Operating Expenses$271.0M$364.0M$457.0M$544.0M$336.0M$378.0M$403.0M$418.0M$462.0M$526.0M
Operating Profit$-201.0M$-321.0M$-362.0M$-426.0M$-336.0M$-378.0M$-389.0M$-391.0M$-426.0M$-472.0M
Operating Margin-287.6%-745.8%-384.0%-361.6%0.0%0.0%-2732.1%-1459.5%-1166.5%-873.9%
Other Income$3.0M$6.0M$16.0M$15.0M$7.0M$22.0M$157.0M$39.0M$1.1B$58.0M
Interest$0$0$0$0$18.0M$0$0$0$0$0
Depreciation$6.0M$6.0M$7.0M$17.0M$19.0M$19.0M$9.0M$7.0M$6.0M$5.0M
Profit Before Tax$-198.0M$-315.0M$-346.0M$-411.0M$-329.0M$-357.0M$-232.0M$-352.0M$718.0M$-414.0M
Tax$0$0$0$0$0$0$0$0$6.2M$250,000
Net Profit$-198.0M$-315.0M$-346.0M$-411.0M$-327.0M$1.6B$-232.0M$-352.0M$674.0M$-413.0M
EPS$-5.07$-6.75$-6.03$-6.61$-4.74$-6.36$-4.23$-6.33$11.64$-7.12
Dividend Payout0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Quarterly Results — Last 12 Quarters (USD millions)

8 duplicate period labels in the source data were collapsed.

MetricSep '23Dec '23Mar '24Jun '24Sep '24Dec '24Mar '25Jun '25Sep '25Dec '25Mar '26Jun '26
Revenue$7.0M$7.0M$8.0M$9.0M$9.0M$11.0M$9.0M$12.0M$13.0M$20.0M$21.0M$45.0M
Operating Expenses$108.0M$113.0M$100.0M$114.0M$112.0M$136.0M$115.0M$140.0M$130.0M$142.0M$131.0M$155.0M
Operating Profit$-101.0M$-106.0M$-92.0M$-106.0M$-103.0M$-125.0M$-107.0M$-127.0M$-117.0M$-122.0M$-110.0M$-111.0M
Operating Margin-1363.7%-1496.2%-1124.3%-1228.3%-1146.9%-1165.3%-1222.0%-1020.1%-907.4%-608.9%-530.3%-247.1%
Interest$0$0$0$0$0$0$0$0$0$0$0$0
Profit Before Tax$-91.0M$-96.0M$-82.0M$-96.0M$1.0B$-105.0M$-89.0M$-112.0M$-103.0M$-109.0M$-99.0M$-101.0M
Tax$0$0$0$0$5.3M$8.4M$0$0$0$930,000$0$0
Net Profit$-91.0M$-96.0M$-82.0M$-96.0M$948.0M$-97.0M$-89.0M$-112.0M$-103.0M$-108.0M$-99.0M$-101.0M
EPS$-1.64$-1.72$-1.45$-1.69$16.22$-1.69$-1.55$-1.93$-1.78$-1.85$-1.69$-1.69

Over the 10 years reported for Agios Pharmaceuticals, Inc., cash stood at $89.0M in the latest year, shareholders' equity was $0, current assets covered current liabilities 11.49 times.

Balance Sheet — 10 Years (USD millions)

Metric2016201720182019202020212022202320242025
Total Assets$619.0M$614.0M$858.0M$891.0M$853.0M$1.4B$1.2B$937.0M$1.7B$1.3B
Current Assets$560.0M$445.0M$614.0M$612.0M$637.0M$1.1B$833.0M$834.0M$966.0M$942.0M
Cash$574.0M$568.0M$805.0M$81.0M$127.0M$203.0M$139.0M$88.0M$76.0M$89.0M
Inventory$-32.0M$-144.0M$1.0M$7.0M$0$0$8.0M$19.0M$28.0M$33.0M
Receivables$8.0M$4.0M$10.0M$15.0M$0$4.0M$2.0M$3.0M$4.0M$11.0M
Fixed Assets$25.0M$24.0M$24.0M$126.0M$116.0M$104.0M$88.0M$70.0M$55.0M$41.0M
Capital Work in Progress$0$0$0$0$0$0$0$0$0$0
Investments$32.0M$144.0M$220.0M$637.0M$543.0M$1.1B$958.0M$718.0M$1.5B$1.1B
Other Assets$0$0$0$0$0$0$0$0$0$0
Total Liabilities$261.0M$239.0M$171.0M$250.0M$453.0M$146.0M$138.0M$126.0M$122.0M$104.0M
Current Liabilities$88.0M$95.0M$94.0M$93.0M$94.0M$60.0M$63.0M$68.0M$81.0M$82.0M
Borrowings$0$0$0$114.0M$105.0M$97.0M$86.0M$72.0M$57.0M$40.0M
Other Liabilities$261.0M$239.0M$171.0M$137.0M$348.0M$49.0M$52.0M$54.0M$65.0M$64.0M
Equity$0$0$0$0$0$0$0$0$0$0
Reserves$359.0M$376.0M$688.0M$641.0M$400.0M$1.3B$1.1B$811.0M$1.5B$1.2B

For Agios Pharmaceuticals, Inc., operating cash flow was positive in 1 of 10 reported years; free cash flow in the latest year was negative at $377.0M; free cash flow was positive in 1 of 10 years.

Cash Flow Statement — 10 Years (USD millions)

Metric2016201720182019202020212022202320242025
Operating Cash Flow$39.0M$-285.0M$-304.0M$-371.0M$-291.0M$-407.0M$-309.0M$-296.0M$-390.0M$-373.0M
Investing Cash Flow$-239.0M$-116.0M$-548.0M$79.0M$62.0M$1.2B$238.0M$239.0M$362.0M$373.0M
Financing Cash Flow$8.0M$15.0M$30.0M$13.0M$251.0M$-765.0M$0$0$0$0
Net Cash Flow$89.0M$-58.0M$-32.0M$10.0M$47.0M$76.0M$-64.0M$-51.0M$-12.0M$13.0M
Free Cash Flow$29.0M$-290.0M$-311.0M$-383.0M$-305.0M$-413.0M$-314.0M$-297.0M$-392.0M$-377.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.03
EV / EBITDA-4.39
FCF Yield-19.24%
Quick Ratio9.79
Interest Coverage—
Return 1Y-9.10%
Return 3Y31.00%
Return 5Y-28.17%

Agios Pharmaceuticals, Inc. (AGIO) financials — frequently asked questions

What is Agios Pharmaceuticals, Inc.'s annual revenue?

Agios Pharmaceuticals, Inc. (AGIO) reported annual revenue of $54.0M in its most recent fiscal year.

What is Agios Pharmaceuticals, Inc.'s net profit?

Agios Pharmaceuticals, Inc. (AGIO) reported a net loss of $413.0M in its most recent fiscal year.

What is AGIO EV/EBITDA?

Agios Pharmaceuticals, Inc.'s enterprise value to EBITDA (EV/EBITDA) ratio is -4.39. A negative value means EBITDA was negative over the period, so the ratio is not a meaningful valuation measure.

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