NYSE · Biotechnology

Alto Neuroscience, Inc. (ANRO) Stock

$21.97 -1.04% NYSE: ANRO Healthcare

Valuation

MetricValue
Price$21.97
Market Cap$862.15M
P/E Ratio-9.71
P/B Ratio4.70
P/S Ratio0.00
EPS (TTM)$0.00
52-Week High$37.48
52-Week Low$5.22
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-46.46%
ROA-33.16%
ROCE18.72%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.03
Current Ratio16.18

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-12.0M$-29.0M$-38.0M$-69.0M$-66.0M
Net Profit$-9.0M$-28.0M$-36.0M$-61.0M$-63.0M
EPS$-0.36$-1.08$-1.35$-2.50$-2.19
Op Margin-5740.9%————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$29.0M$51.0M$87.0M$178.0M$185.0M
Total Liabilities$41.0M$89.0M$158.0M$26.0M$34.0M
Cash$26.0M$48.0M$83.0M$168.0M$176.0M
Borrowings$38.0M$82.0M$10.0M$17.0M$4.0M

Latest News

Alto Neuroscience Prices $100 Million Stock Offering MT Newswires · Jul 13, 2026 Alto Neuroscience Announces Pricing of $100.0 Million Underwritten Registered Direct Offering of Common Stock Business Wire · Jul 13, 2026 Is Alto Neuroscience, Inc. (ANRO) Stock Positioned for Growth With New Insights Into Anhedonia Treatment? Insider Monkey · Jul 2, 2026 Alto Neuroscience Highlights Nature Medicine Publication Demonstrating Significant Effects of Pramipexole on Anhedonia Business Wire · Jun 15, 2026 Alpha Wave Global Initiates COPT Defense Properties Position, According to Recent SEC Filing Motley Fool · May 27, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-9.0M$-20.0M$-33.0M$-47.0M$-52.0M
Investing Cash Flow$-1.0M$-1.0M$-1.0M$-4.0M$0
Financing Cash Flow$0$0$-2.0M$-3.0M$0
Net Cash Flow$22.0M$23.0M$34.0M$86.0M$8.0M
Free Cash Flow$-10.0M$-21.0M$-34.0M$-49.0M$-52.0M

Valuation & Return Ratios

MetricValue
PEG Ratio1.96
EV / EBITDA-7.47
FCF Yield-8.14%
Quick Ratio14.85
Interest Coverage19.66
Return 1Y774.59%
Return 3Y—
Return 5Y—

Ownership

Insiders Held4.11%
Institutions Held74.13%
Institutions Float Held77.32%
Institutional HolderSharesReport Date
Alpha Wave Global, LP3,707,7572026-03-31
Commodore Capital Lp2,723,1962026-03-31
Vestal Point Capital, LP2,064,0752026-03-31
Perceptive Advisors Llc2,009,8932026-03-31
Spruce Street Capital LP1,325,2102026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ACIUAC Immune SA $2.42 -3.20% -5.24 $246.29M 0.00%
ALDXAldeyra Therapeutics, Inc. $0.65 +0.68% -3.02 $39.19M 0.00%
AMRNAmarin Corporation plc $14.58 +0.80% -9.00 $301.45M 0.00%
CLLSCellectis S.A. $2.81 -2.26% -4.14 $282.17M 0.00%
CTNMContineum Therapeutics, Inc. $8.31 -1.01% -7.58 $273.89M 0.00%

About Alto Neuroscience, Inc.

Alto Neuroscience, Inc. is led by CEO Amit Etkin, employs 76 people, headquartered in US, publicly traded since 2024.

Alto Neuroscience, Inc. (ANRO) stock trades at $21.97 with a market capitalization of $862.15M. The stock is valued at a negative price-to-earnings (P/E) ratio of -9.71, reflecting a net loss over the last twelve months, price-to-book of 4.70, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $5.22 and $37.48, and currently trades 41.4% below its 52-week high.

On profitability, Alto Neuroscience, Inc. generates a return on equity (ROE) of -46.46% (negative, reflecting a net loss), return on capital employed of 18.72%.

Alto Neuroscience, Inc. by the numbers, 2021–2025

Between 2021 and 2025 Alto Neuroscience, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-63.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-84.0M.

Borrowings fell from $38.0M to $4.0M, cash from operations was $-52.0M in the latest year, positive in 0 of the last 5.

Return on equity has averaged 23.3% over five years, and was -41.7% in the most recent year.

The share price itself has compounded at —% a year over five years, —% over three, 795.9% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

Alto Neuroscience, Inc. (ANRO) — frequently asked questions

What is Alto Neuroscience, Inc. (ANRO) stock price today?

Alto Neuroscience, Inc. (ANRO) is currently trading at $21.97, down 1.04% today.

What is ANRO P/E ratio?

Alto Neuroscience, Inc.'s P/E ratio is -9.71. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is ANRO return on equity (ROE)?

Alto Neuroscience, Inc.'s return on equity (ROE) is -46.46%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is Alto Neuroscience, Inc.'s market cap?

Alto Neuroscience, Inc. has a market capitalization of $862.15M.

Does ANRO pay a dividend?

Alto Neuroscience, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does ANRO carry?

Alto Neuroscience, Inc. has a debt-to-equity ratio of 0.03. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is ANRO's profit margin?

Alto Neuroscience, Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is ANRO in?

Alto Neuroscience, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is ANRO listed on?

Alto Neuroscience, Inc. trades on NYSE under the ticker ANRO.

What is ANRO's 52-week range?

Over the last year Alto Neuroscience, Inc. has traded between $5.22 and $37.48.

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Screens ANRO currently matches

On the figures above, Alto Neuroscience, Inc. passes the filters for 8 of our ready-made screens, among them Small Cap Stocks, Debt Free Stocks Under $100, Debt Free Stocks. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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