NASDAQ · Biotechnology

AN2 Therapeutics, Inc. (ANTX) Stock

$3.55 -2.47% NASDAQ: ANTX Healthcare

Valuation

MetricValue
Price$3.55
Market Cap$133.96M
P/E Ratio-5.24
P/B Ratio3.31
P/S Ratio0.00
EPS (TTM)$0.00
52-Week High$7.19
52-Week Low$1.00
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-53.52%
ROA-44.41%
ROCE-51.01%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.00
Current Ratio6.67

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-22.0M$-42.0M$-70.0M$-55.0M$-38.0M
Net Profit$-22.0M$-41.0M$-65.0M$-51.0M$-35.0M
EPS$-1.50$-2.79$-2.74$-1.72$-1.16
Op Margin—————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$65.0M$103.0M$139.0M$92.0M$62.0M
Total Liabilities$3.0M$7.0M$14.0M$10.0M$9.0M
Cash$12.0M$27.0M$16.0M$21.0M$20.0M
Borrowings$0$0$0$0$0

Latest News

AN2 Therapeutics Says Chagas Disease Drug Shows Positive Preclinical, Early Human Data MT Newswires · Jun 4, 2026 AN2 Therapeutics Reports Positive Enabling Data Supporting Advancement of Oral AN2-502998 to Phase 2 Study for Chronic Chagas Disease Business Wire · Jun 4, 2026 Correction: Leerink Partners Upgrades AN2 Therapeutics to Outperform From Market Perform, Adjusts Price Target to $9 From $1 MT Newswires · May 14, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-20.0M$-33.0M$-53.0M$-49.0M$-30.0M
Investing Cash Flow$-50.0M$-22.0M$-43.0M$55.0M$28.0M
Financing Cash Flow$-1.0M$0$0$0$0
Net Cash Flow$8.0M$15.0M$-12.0M$6.0M$-1.0M
Free Cash Flow$-20.0M$-33.0M$-53.0M$-49.0M$-30.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.37
EV / EBITDA-4.20
FCF Yield-15.19%
Quick Ratio14.32
Interest Coverage—
Return 1Y344.86%
Return 3Y-39.82%
Return 5Y—

Ownership

Insiders Held18.99%
Institutions Held70.60%
Institutions Float Held87.14%
Institutional HolderSharesReport Date
Vivo Capital, LLC3,153,6402026-03-31
Commodore Capital Lp2,333,7132026-03-31
Millennium Management Llc2,222,5022026-03-31
Spruce Street Capital LP1,661,0732026-03-31
Almitas Capital LLC1,479,1292026-03-31

About AN2 Therapeutics, Inc.

AN2 Therapeutics, Inc. is led by CEO Eric E. Easom, employs 22 people, headquartered in US, publicly traded since 2022.

AN2 Therapeutics, Inc. (ANTX) stock trades at $3.55 with a market capitalization of $133.96M. The stock is valued at a negative price-to-earnings (P/E) ratio of -5.24, reflecting a net loss over the last twelve months, price-to-book of 3.31, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $1.00 and $7.19, and currently trades 50.6% below its 52-week high.

On profitability, AN2 Therapeutics, Inc. generates a return on equity (ROE) of -53.52% (negative, reflecting a net loss), return on capital employed of -51.01%.

AN2 Therapeutics, Inc. by the numbers, 2019–2025

Between 2019 and 2025 AN2 Therapeutics, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-35.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-36.0M.

Borrowings fell from $1.0M to $0, cash from operations was $-30.0M in the latest year, positive in 0 of the last 7.

Return on equity has averaged -51.8% over five years, and was -66.0% in the most recent year.

The share price itself has compounded at —% a year over five years, -10.9% over three, 362.6% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

AN2 Therapeutics, Inc. (ANTX) — frequently asked questions

What is AN2 Therapeutics, Inc. (ANTX) stock price today?

AN2 Therapeutics, Inc. (ANTX) is currently trading at $3.55, down 2.47% today.

What is ANTX P/E ratio?

AN2 Therapeutics, Inc.'s P/E ratio is -5.24. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is ANTX return on equity (ROE)?

AN2 Therapeutics, Inc.'s return on equity (ROE) is -53.52%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is AN2 Therapeutics, Inc.'s market cap?

AN2 Therapeutics, Inc. has a market capitalization of $133.96M.

Does ANTX pay a dividend?

AN2 Therapeutics, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does ANTX carry?

AN2 Therapeutics, Inc. has a debt-to-equity ratio of 0.00. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is ANTX's profit margin?

AN2 Therapeutics, Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is ANTX in?

AN2 Therapeutics, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is ANTX listed on?

AN2 Therapeutics, Inc. trades on NASDAQ under the ticker ANTX.

What is ANTX's 52-week range?

Over the last year AN2 Therapeutics, Inc. has traded between $1.00 and $7.19.

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Screens ANTX currently matches

On the figures above, AN2 Therapeutics, Inc. passes the filters for 5 of our ready-made screens, among them Penny Stocks, Stocks Under $5, Debt Free Stocks Under $100. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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