Bicycle Therapeutics plc most recently reported annual revenue of $73.0M, a net loss of $219.0M. Revenue grew at an average annual rate of 48.8% over the last 5 fiscal years. See the full income statement, balance sheet, and cash flow statement below, plus valuation and return ratios.
Bicycle Therapeutics plc: net profit was positive in 0 of 10 reported years; operating margin moved from -787.0% to -341.3%, a shift of +445.8 percentage points; the most recent year shows a net loss of $219.0M.
Income Statement — 10 Years (USD millions)
Metric
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
Revenue
$0
$2.0M
$7.0M
$14.0M
$10.0M
$12.0M
$14.0M
$27.0M
$35.0M
$73.0M
Operating Expenses
$13.0M
$18.0M
$29.0M
$40.0M
$62.0M
$77.0M
$131.0M
$217.0M
$245.0M
$320.0M
Operating Profit
$-13.0M
$-16.0M
$-22.0M
$-26.0M
$-52.0M
$-66.0M
$-117.0M
$-190.0M
$-210.0M
$-248.0M
Operating Margin
0.0%
-787.0%
-304.7%
-190.6%
-500.1%
-561.0%
-806.6%
-704.1%
-595.0%
-341.3%
Other Income
$0
$0
$0
$-5.0M
$0
$-3.0M
$2.0M
$11.0M
$36.0M
$29.0M
Interest
$0
$0
$0
$0
$0
$3.0M
$3.0M
$3.0M
$2.0M
$0
Depreciation
$0
$0
$1.0M
$1.0M
$1.0M
$1.0M
$4.0M
$7.0M
$7.0M
$6.0M
Profit Before Tax
$-14.0M
$-16.0M
$-22.0M
$-31.0M
$-52.0M
$-68.0M
$-114.0M
$-179.0M
$-174.0M
$-219.0M
Tax
$150,000
$140,000
$1.8M
$820,000
$1.4M
$2.4M
$1.3M
$-810,000
$2.7M
$-70,000
Net Profit
$-14.0M
$-16.0M
$-22.0M
$-31.0M
$-51.0M
$-67.0M
$-113.0M
$-181.0M
$-169.0M
$-219.0M
EPS
$-0.76
$-1.22
$-1.64
$-2.77
$-2.66
$-2.67
$-3.80
$-5.08
$-2.90
$-3.16
Dividend Payout
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
0.0%
Quarterly Results — Last 12 Quarters (USD millions)
8 duplicate period labels in the source data were collapsed.
Metric
Jun '23
Sep '23
Dec '23
Mar '24
Jun '24
Sep '24
Dec '24
Mar '25
Jun '25
Sep '25
Dec '25
Mar '26
Revenue
$11.0M
$5.0M
$5.0M
$20.0M
$9.0M
$3.0M
$4.0M
$10.0M
$3.0M
$12.0M
$48.0M
$1.0M
Operating Expenses
$55.0M
$56.0M
$60.0M
$51.0M
$56.0M
$67.0M
$71.0M
$80.0M
$90.0M
$77.0M
$73.0M
$66.0M
Operating Profit
$-43.0M
$-51.0M
$-54.0M
$-32.0M
$-47.0M
$-64.0M
$-68.0M
$-70.0M
$-87.0M
$-66.0M
$-25.0M
$-66.0M
Operating Margin
-378.3%
-949.1%
-1017.4%
-162.4%
-498.3%
-2385.9%
-1824.8%
-703.7%
-2965.8%
-558.6%
-51.4%
-7394.5%
Interest
$1.0M
$1.0M
$1.0M
$1.0M
$1.0M
$0
$0
$0
$0
$0
$0
$0
Profit Before Tax
$-43.0M
$-48.0M
$-49.0M
$-27.0M
$-40.0M
$-54.0M
$-53.0M
$-62.0M
$-79.0M
$-59.0M
$-19.0M
$-61.0M
Tax
$1.2M
$-4.8M
$-660,000
$1.3M
$-290,000
$6.4M
$2.0M
$1.8M
$290,000
$-350,000
$-6.7M
$-280,000
Net Profit
$-43.0M
$-50.0M
$-49.0M
$-27.0M
$-40.0M
$-51.0M
$-52.0M
$-61.0M
$-79.0M
$-59.0M
$-20.0M
$-61.0M
EPS
$-1.41
$-1.26
$-1.16
$-0.62
$-0.77
$-0.74
$-0.74
$-0.88
$-1.14
$-0.85
$-0.29
$-0.87
Over the 10 years reported for Bicycle Therapeutics plc, cash stood at $628.0M in the latest year, shareholders' equity was $1.0M, current assets covered current liabilities 11.98 times.
Balance Sheet — 10 Years (USD millions)
Metric
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
Total Assets
$12.0M
$74.0M
$82.0M
$110.0M
$161.0M
$480.0M
$411.0M
$595.0M
$957.0M
$718.0M
Current Assets
$11.0M
$72.0M
$77.0M
$104.0M
$156.0M
$459.0M
$369.0M
$562.0M
$929.0M
$683.0M
Cash
$9.0M
$68.0M
$63.0M
$92.0M
$136.0M
$439.0M
$339.0M
$526.0M
$880.0M
$628.0M
Inventory
$0
$0
$0
$0
$0
$0
$0
$0
$0
$0
Receivables
$1.0M
$3.0M
$11.0M
$7.0M
$15.0M
$12.0M
$21.0M
$24.0M
$36.0M
$36.0M
Fixed Assets
$1.0M
$1.0M
$2.0M
$4.0M
$4.0M
$18.0M
$33.0M
$28.0M
$17.0M
$22.0M
Capital Work in Progress
$0
$0
$0
$0
$0
$0
$0
$0
$0
$0
Investments
$0
$0
$0
$0
$0
$0
$0
$1.0M
$1.0M
$0
Other Assets
$0
$0
$0
$0
$0
$0
$0
$0
$0
$0
Total Liabilities
$4.0M
$121.0M
$151.0M
$17.0M
$66.0M
$134.0M
$140.0M
$224.0M
$164.0M
$108.0M
Current Liabilities
$4.0M
$9.0M
$9.0M
$9.0M
$23.0M
$36.0M
$53.0M
$70.0M
$67.0M
$57.0M
Borrowings
$0
$0
$0
$2.0M
$16.0M
$44.0M
$44.0M
$45.0M
$9.0M
$18.0M
Other Liabilities
$4.0M
$121.0M
$151.0M
$15.0M
$50.0M
$89.0M
$96.0M
$179.0M
$154.0M
$90.0M
Equity
$0
$0
$0
$0
$0
$0
$0
$1.0M
$1.0M
$1.0M
Reserves
$8.0M
$-47.0M
$-70.0M
$93.0M
$95.0M
$346.0M
$271.0M
$371.0M
$793.0M
$610.0M
For Bicycle Therapeutics plc, operating cash flow was positive in 0 of 10 reported years; free cash flow in the latest year was negative at $253.0M; free cash flow was positive in 0 of 10 years.