NASDAQ · Biotechnology

LeonaBio, Inc. (LONA) Stock

$4.84 -2.62% NASDAQ: LONA Healthcare

Valuation

MetricValue
Price$4.84
Market Cap$19.09M
P/E Ratio-0.16
P/B Ratio0.68
P/S Ratio0.00
EPS (TTM)$-24.70
52-Week High$11.91
52-Week Low$2.21
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-411.58%
ROA-248.63%
ROCE-250.70%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.02
Current Ratio1.85

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-64.0M$-104.0M$-125.0M$-101.0M$-102.0M
Net Profit$-55.0M$-96.0M$-118.0M$-97.0M$-106.0M
EPS$-14.90$-25.30$-30.90$-25.20$-24.70
Op Margin—————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$332.0M$258.0M$160.0M$59.0M$92.0M
Total Liabilities$11.0M$23.0M$30.0M$14.0M$64.0M
Cash$111.0M$96.0M$91.0M$48.0M$69.0M
Borrowings$2.0M$2.0M$2.0M$1.0M$1.0M

Latest News

Immuneering Names Andrew Gengos as CFO MT Newswires · Jun 15, 2026 LeonaBio Presents on ATH-1105 at 5th Annual ALS Drug Development Summit GlobeNewswire · Jun 4, 2026 LeonaBio to Participate in Upcoming Medical and Industry Meetings in June GlobeNewswire · May 27, 2026 LeonaBio Reports First Quarter 2026 Financial Results and Provides Business Update GlobeNewswire · May 7, 2026 LeonaBio Enhances Board of Directors with Appointments of Fred Callori, J.D., Natalie Holles and Peter B. Silverman, J.D. GlobeNewswire · May 7, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-43.0M$-72.0M$-101.0M$-97.0M$-46.0M
Investing Cash Flow$-6.0M$57.0M$95.0M$55.0M$-16.0M
Financing Cash Flow$0$0$0$0$82.0M
Net Cash Flow$50.0M$-14.0M$-5.0M$-42.0M$21.0M
Free Cash Flow$-45.0M$-74.0M$-101.0M$-97.0M$-46.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.00
EV / EBITDA0.20
FCF Yield-294.58%
Quick Ratio7.01
Interest Coverage—
Return 1Y127.27%
Return 3Y-70.68%
Return 5Y-90.55%

Ownership

Insiders Held4.51%
Institutions Held70.41%
Institutions Float Held73.74%
Institutional HolderSharesReport Date
Perceptive Advisors Llc1,859,3222026-03-31
Adar1 Capital Management, LLC 727,4812026-03-31
Acorn Capital Advisors, LLC 634,5392026-03-31
Commodore Capital Lp464,3982026-03-31
NEA Management Company, LLC464,3982026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ADTX $0.01 -77.22% -0.01 $318 0.00%
APLMApollomics Inc. $21.84 -2.17% -2.85 $63.66M 0.00%
CRISCuris, Inc. $0.39 -4.59% -0.06 $753285 0.00%
CTXRCitius Pharmaceuticals, Inc. $0.40 +8.79% -0.25 $11.07M 0.00%
DAREDare Bioscience, Inc. $0.65 -0.89% -0.94 $9.68M 0.00%

About LeonaBio, Inc.

LeonaBio, Inc. is led by CEO Mark J. Litton, employs 26 people, headquartered in US, publicly traded since 2020.

LeonaBio, Inc. (LONA) stock trades at $4.84 with a market capitalization of $19.09M. The stock is valued at a negative price-to-earnings (P/E) ratio of -0.16, reflecting a net loss over the last twelve months, price-to-book of 0.68, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $2.21 and $11.91, and currently trades 59.4% below its 52-week high.

On profitability, LeonaBio, Inc. generates a return on equity (ROE) of -411.58% (negative, reflecting a net loss), return on capital employed of -250.70%.

LeonaBio, Inc. by the numbers, 2018–2025

Between 2018 and 2025 LeonaBio, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-106.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-142.0M.

Borrowings held roughly flat from $1.0M to $1.0M, cash from operations was $-46.0M in the latest year, positive in 0 of the last 8.

Return on equity has averaged -148.6% over five years, and was -378.6% in the most recent year.

The share price itself has compounded at -46.1% a year over five years, -34.2% over three, 177.0% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

LeonaBio, Inc. (LONA) — frequently asked questions

What is LeonaBio, Inc. (LONA) stock price today?

LeonaBio, Inc. (LONA) is currently trading at $4.84, down 2.62% today.

What is LONA P/E ratio?

LeonaBio, Inc.'s P/E ratio is -0.16. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is LONA return on equity (ROE)?

LeonaBio, Inc.'s return on equity (ROE) is -411.58%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is LeonaBio, Inc.'s market cap?

LeonaBio, Inc. has a market capitalization of $19.09M.

Does LONA pay a dividend?

LeonaBio, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does LONA carry?

LeonaBio, Inc. has a debt-to-equity ratio of 0.02. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is LONA's profit margin?

LeonaBio, Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is LONA in?

LeonaBio, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is LONA listed on?

LeonaBio, Inc. trades on NASDAQ under the ticker LONA.

What is LONA's 52-week range?

Over the last year LeonaBio, Inc. has traded between $2.21 and $11.91.

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Screens LONA currently matches

On the figures above, LeonaBio, Inc. passes the filters for 3 of our ready-made screens, among them Penny Stocks, Debt Free Stocks Under $100, Nano Cap Stocks. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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