NASDAQ · Biotechnology

ProMIS Neurosciences Inc. (PMN) Stock

$8.34 -7.13% NASDAQ: PMN Healthcare

Valuation

MetricValue
Price$8.34
Market Cap$74.79M
P/E Ratio-0.55
P/B Ratio1.73
P/S Ratio0.00
EPS (TTM)$-22.61
52-Week High$27.40
52-Week Low$6.27
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-143.09%
ROA-74.48%
ROCE-87.79%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.00
Current Ratio0.90

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-11.0M$-23.4B$-19.0M$-17.0M$-40.0M
Net Profit$-12.0M$-18.1B$-18.0M$3.0M$-40.0M
EPS$-51.77$-60.25$-35.50$2.75$-22.61
Op Margin-63350.5%————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$22.0M$13.0M$14.0M$19.0M$9.0M
Total Liabilities$15.0M$15.0M$10.0M$2.0M$10.0M
Cash$21.0M$11.0M$13.0M$13.0M$6.0M
Borrowings$5.0M$0$0$0$0

Latest News

Promis Reports No ARIA-E in PMN310 Alzheimer’s Trial Interim Data MarketBeat · Jul 28, 2026 Chardan Adjusts Price Target on ProMIS Neurosciences to $33 From $20, Maintains Buy Rating MT Newswires · Jul 28, 2026 ProMIS Neurosciences Shares Climb on Positive Interim Alzheimer’s Trial Safety Results InvestorsHub · Jul 28, 2026 ProMIS Neurosciences Says PMN310 Alzheimer Drug Shows Positive Interim Safety, Biomarker Data MT Newswires · Jul 28, 2026 ProMIS Neurosciences Reports Positive Blinded Six-Month Interim Safety and Biomarker Data for PMN310 in the PRECISE-AD Phase 1b Alzheimer’s Disease Trial GlobeNewswire · Jul 28, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-9.0M$-23.0M$-11.0M$-27.0M$-28.0M
Investing Cash Flow$0$0$0$0$0
Financing Cash Flow$0$2.0M$0$0$0
Net Cash Flow$16.0M$-15.0M$7.0M$1.0M$-7.0M
Free Cash Flow$-9.0M$-23.0M$-11.0M$-27.0M$-28.0M

Valuation & Return Ratios

MetricValue
PEG Ratio0.00
EV / EBITDA-0.72
FCF Yield-49.99%
Quick Ratio7.85
Interest Coverage—
Return 1Y27.32%
Return 3Y-80.06%
Return 5Y-93.78%

Ownership

Insiders Held11.85%
Institutions Held74.37%
Institutions Float Held84.36%
Institutional HolderSharesReport Date
Janus Henderson Group PLC1,292,7572026-03-31
Deep Track Capital, Lp835,6552026-03-31
Wellington Management Group, LLP696,3782026-03-31
Trails Edge Capital Partners, LP557,1032026-03-31
Ally Bridge Group (NY) LLC414,2192026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ADAPAdaptimmune Therapeutics plc $0.05 -3.00% -0.16 $75.16M 0.00%
ANLAdlai Nortye Ltd. $13.26 +2.00% -8.19 $703.84M 0.00%
BRTXBioRestorative Therapies, Inc. $1.62 +8.00% -0.10 $2.24M 0.00%
EDSAEdesa Biotech, Inc. $2.77 +0.36% -2.28 $26.68M 0.00%
ERNAErnexa Therapeutics Inc. $2.07 -0.48% -0.15 $3.37M 0.00%

About ProMIS Neurosciences Inc.

ProMIS Neurosciences Inc. is led by CEO Neil K. Warma, employs 7 people, headquartered in CA, publicly traded since 2007.

ProMIS Neurosciences Inc. (PMN) stock trades at $8.34 with a market capitalization of $74.79M. The stock is valued at a negative price-to-earnings (P/E) ratio of -0.55, reflecting a net loss over the last twelve months, price-to-book of 1.73, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $6.27 and $27.40, and currently trades 69.6% below its 52-week high.

On profitability, ProMIS Neurosciences Inc. generates a return on equity (ROE) of -143.09% (negative, reflecting a net loss), return on capital employed of -87.79%.

ProMIS Neurosciences Inc. by the numbers, 2016–2025

Between 2016 and 2025 ProMIS Neurosciences Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-40.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-43.0M.

Borrowings stand at $0, cash from operations was $-28.0M in the latest year, positive in 0 of the last 10.

Return on equity has averaged 181299.5% over five years, and was 4000.0% in the most recent year.

The share price itself has compounded at —% a year over five years, —% over three, —% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

ProMIS Neurosciences Inc. (PMN) — frequently asked questions

What is ProMIS Neurosciences Inc. (PMN) stock price today?

ProMIS Neurosciences Inc. (PMN) is currently trading at $8.34, down 7.13% today.

What is PMN P/E ratio?

ProMIS Neurosciences Inc.'s P/E ratio is -0.55. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is PMN return on equity (ROE)?

ProMIS Neurosciences Inc.'s return on equity (ROE) is -143.09%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is ProMIS Neurosciences Inc.'s market cap?

ProMIS Neurosciences Inc. has a market capitalization of $74.79M.

Does PMN pay a dividend?

ProMIS Neurosciences Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does PMN carry?

ProMIS Neurosciences Inc. has a debt-to-equity ratio of 0.00. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is PMN's profit margin?

ProMIS Neurosciences Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is PMN in?

ProMIS Neurosciences Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is PMN listed on?

ProMIS Neurosciences Inc. trades on NASDAQ under the ticker PMN.

What is PMN's 52-week range?

Over the last year ProMIS Neurosciences Inc. has traded between $6.27 and $27.40.

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Screens PMN currently matches

On the figures above, ProMIS Neurosciences Inc. passes the filters for 4 of our ready-made screens, among them Day Losers Stocks, Debt Free Stocks Under $100, Micro Cap Stocks. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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