NASDAQ · Biotechnology

ALNY (ALNY) Stock

$246.11 +2.25% NASDAQ: ALNY Healthcare

Valuation

MetricValue
Price$246.11
Market Cap$32.93B
P/E Ratio73.95
P/B Ratio36.61
P/S Ratio9.21
EPS (TTM)$3.99
52-Week High$495.55
52-Week Low$228.08
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE90.36%
ROA10.06%
ROCE63.62%
Gross Margin13.52%
Operating Margin13.52%
Net Margin13.46%
Debt/Equity1.18
Current Ratio2.76

Annual Financials (USD)

Metric20212022202320242025
Revenue$844.0M$1.0B$1.8B$2.2B$3.7B
Operating Profit$-709.0M$-785.0M$-282.0M$-177.0M$502.0M
Net Profit$-853.0M$-1.1B$-440.0M$-278.0M$314.0M
EPS$-7.20$-9.30$-3.52$-2.18$2.33
Op Margin-83.9%-75.7%-15.4%-7.9%13.5%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$3.6B$3.5B$3.8B$4.2B$5.0B
Total Liabilities$3.1B$3.7B$4.1B$4.2B$4.2B
Cash$820.0M$866.0M$813.0M$966.0M$1.7B
Borrowings$998.0M$1.3B$1.3B$2.7B$1.3B

Latest News

Is Alnylam Pharmaceuticals (ALNY) Cheap As Rival Trial Failure Shifts ATTR CM Expectations? Simply Wall St. · Jul 11, 2026 Ionis Pharmaceuticals Drops Another 9% as Bad News Piles Up 24/7 Wall St. · Jul 10, 2026 Is Rival ATTR-CM Trial Failure and New AI Deals Altering The Investment Case For Alnylam (ALNY)? Simply Wall St. · Jul 10, 2026 Alnylam (ALNY) Gets An Opening In ATTR CM As Rival Trial Fails Simply Wall St. · Jul 10, 2026 Beyond The Breakout Drug: Is BridgeBio Pharma Stock A Buy On Its Next Act? Trefis · Jul 10, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-642.0M$-541.0M$104.0M$-8.0M$524.0M
Investing Cash Flow$-350.0M$97.0M$-399.0M$-151.0M$378.0M
Financing Cash Flow$501.0M$-88.0M$25.0M$-9.0M$-8.0M
Net Cash Flow$323.0M$46.0M$-54.0M$154.0M$690.0M
Free Cash Flow$-718.0M$-613.0M$42.0M$-43.0M$465.0M

Valuation & Return Ratios

MetricValue
PEG Ratio34.75
EV / EBITDA70.03
FCF Yield1.62%
Quick Ratio3.06
Interest Coverage1.98
Return 1Y-47.58%
Return 3Y21.93%
Return 5Y17.20%

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ARGXargenx SE $862.93 +0.41% 48.25 $53.99B 0.00%
BDX $187.12 -0.53% 57.29 $51.56B 2.21%
CAH $239.35 +2.02% 32.79 $56.06B 0.86%
CI $283.06 +2.53% 11.58 $74.80B 2.22%
COR $331.22 +2.35% 23.93 $64.44B 0.74%

About ALNY

ALNY is led by CEO Yvonne L. Greenstreet, employs 2,230 people, headquartered in Cambridge, US, publicly traded since 2004.

ALNY stock trades at $246.11 with a market capitalization of $32.93B. The stock is valued at a price-to-earnings (P/E) ratio of 73.95, price-to-book of 36.61, price-to-sales of 9.21. Over the past 52 weeks the stock has ranged between $228.08 and $495.55, and currently trades 50.3% below its 52-week high.

On profitability, ALNY generates a return on equity (ROE) of 90.36% — well above the market average, a sign of a high-quality business, return on capital employed of 63.62%, an operating margin of 13.52%, a net profit margin of 13.46%.

In its most recent fiscal year, ALNY reported annual revenue of $3.7B, net profit of $314.0M, revenue has compounded at 49.8% a year over the last five years.

The balance sheet shows a debt-to-equity ratio of 1.18, a current ratio of 2.76, total assets of $5.0B, $1.7B in cash and equivalents.

ALNY has a beta of 0.27 (less volatile than the overall market).

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