NASDAQ · Biotechnology

Actuate Therapeutics, Inc. (ACTU) Stock

$0.48 -7.94% NASDAQ: ACTU Healthcare

Valuation

MetricValue
Price$0.48
Market Cap$11.41M
P/E Ratio-0.92
P/B Ratio19.77
P/S Ratio0.00
EPS (TTM)$-1.06
52-Week High$8.49
52-Week Low$0.43
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-346.18%
ROA-393.39%
ROCE-275.00%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.41
Current Ratio2.33

Annual Financials (USD)

Metric2022202320242025
Revenue$0$0$0$0
Operating Profit$-20.0M$-25.0M$-25.0M$-22.0M
Net Profit$-20.0M$-25.0M$-27.0M$-22.0M
EPS$-1.34$-1.65$-3.26$-1.06
Op Margin————

Balance Sheet (USD)

Metric2022202320242025
Total Assets$20.0M$3.0M$9.0M$14.0M
Total Liabilities$6.0M$103.0M$9.0M$6.0M
Cash$20.0M$3.0M$9.0M$13.0M
Borrowings$0$0$0$0

Latest News

Actuate Therapeutics Says Elraglusib to be Evaluated in Phase 1/2 Trial to Find Treatments for Pediatric Neuroblastoma MT Newswires · Jun 9, 2026 Actuate Therapeutics’ Elraglusib Selected for Evaluation in BEACON2 Trial for High-Risk Pediatric Neuroblastoma GlobeNewswire · Jun 9, 2026 Actuate Therapeutics Announces ASCO Poster Presentations Demonstrating Compelling Clinical and Biomarker Data for Elraglusib in First-Line Metastatic Pancreatic Cancer GlobeNewswire · Jun 1, 2026 Actuate Therapeutics Announces FDA Clearance of IND for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program GlobeNewswire · May 11, 2026 Actuate Therapeutics Announces Key Appointment of Industry Veteran to Board of Directors GlobeNewswire · May 6, 2026

Cash Flow (USD)

Metric2022202320242025
Operating Cash Flow$-18.0M$-22.0M$-22.0M$-19.0M
Investing Cash Flow$0$0$0$0
Financing Cash Flow$0$0$-2.0M$0
Net Cash Flow$1.0M$-17.0M$6.0M$5.0M
Free Cash Flow$-18.0M$-22.0M$-22.0M$-19.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.01
EV / EBITDA-0.76
FCF Yield-101.23%
Quick Ratio1.25
Interest Coverage-1025.81
Return 1Y-71.86%
Return 3Y—
Return 5Y—

Ownership

Insiders Held14.84%
Institutions Held58.20%
Institutions Float Held68.34%
Institutional HolderSharesReport Date
Bios Capital Management, LP 10,049,9962026-03-31
Voss Capital, LP1,725,0002026-03-31
Blackrock Inc.427,1532026-03-31
Vanguard Capital Management LLC400,5292026-03-31
Geode Capital Management, LLC228,3312026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ALECAlector, Inc. $1.83 +0.00% -1.74 $204.33M 0.00%
APLTApplied Therapeutics, Inc. $0.10 +0.00% -0.24 $14.86M 0.00%
ELTXElicio Therapeutics, Inc. $1.90 -2.06% -0.89 $36.23M 0.00%
MCRBSeres Therapeutics, Inc. $2.09 -1.88% -1.21 $20.78M 0.00%
MOLNMolecular Partners AG $3.91 -2.25% -2.08 $146.67M 0.00%

About Actuate Therapeutics, Inc.

Actuate Therapeutics, Inc. is led by CEO Daniel Schmitt, employs 10 people, headquartered in US, publicly traded since 2024.

Actuate Therapeutics, Inc. (ACTU) stock trades at $0.48 with a market capitalization of $11.41M. The stock is valued at a negative price-to-earnings (P/E) ratio of -0.92, reflecting a net loss over the last twelve months, price-to-book of 19.77, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $0.43 and $8.49, and currently trades 94.3% below its 52-week high.

On profitability, Actuate Therapeutics, Inc. generates a return on equity (ROE) of -346.18% (negative, reflecting a net loss), return on capital employed of -275.00%.

Actuate Therapeutics, Inc. by the numbers, 2022–2025

Between 2022 and 2025 Actuate Therapeutics, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-22.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-21.0M.

Borrowings stand at $0, cash from operations was $-19.0M in the latest year, positive in 0 of the last 4.

Return on equity has averaged -127.8% over five years, and was -275.0% in the most recent year.

The share price itself has compounded at —% a year over five years, —% over three, —% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

Actuate Therapeutics, Inc. (ACTU) — frequently asked questions

What is Actuate Therapeutics, Inc. (ACTU) stock price today?

Actuate Therapeutics, Inc. (ACTU) is currently trading at $0.48, down 7.94% today.

What is ACTU P/E ratio?

Actuate Therapeutics, Inc.'s P/E ratio is -0.92. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is ACTU return on equity (ROE)?

Actuate Therapeutics, Inc.'s return on equity (ROE) is -346.18%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is Actuate Therapeutics, Inc.'s market cap?

Actuate Therapeutics, Inc. has a market capitalization of $11.41M.

Does ACTU pay a dividend?

Actuate Therapeutics, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does ACTU carry?

Actuate Therapeutics, Inc. has a debt-to-equity ratio of 0.41. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is ACTU's profit margin?

Actuate Therapeutics, Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is ACTU in?

Actuate Therapeutics, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is ACTU listed on?

Actuate Therapeutics, Inc. trades on NASDAQ under the ticker ACTU.

What is ACTU's 52-week range?

Over the last year Actuate Therapeutics, Inc. has traded between $0.43 and $8.49.

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Screens ACTU currently matches

On the figures above, Actuate Therapeutics, Inc. passes the filters for 4 of our ready-made screens, among them Day Losers Stocks, Penny Stocks, Stocks Under $1. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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Data for information only, not investment advice. Figures may be delayed or inaccurate; verify against company filings. See our disclaimer.