NASDAQ · Biotechnology

Praxis Precision Medicines, Inc. (PRAX) Stock

$259.86 -1.40% NASDAQ: PRAX Healthcare

Valuation

MetricValue
Price$259.86
Market Cap$7.24B
P/E Ratio-22.82
P/B Ratio6.42
P/S Ratio0.00
EPS (TTM)$-13.48
52-Week High$392.70
52-Week Low$50.31
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-34.15%
ROA-24.40%
ROCE-28.20%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.00
Current Ratio10.18

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$2.0M$9.0M$0
Operating Profit$-167.0M$-215.0M$-126.0M$-200.0M$-326.0M
Net Profit$-167.0M$-214.0M$-123.0M$-183.0M$-303.0M
EPS$-58.96$-69.33$-18.69$-10.21$-13.48
Op Margin——-5164.4%-2340.3%—

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$293.0M$115.0M$88.0M$483.0M$938.0M
Total Liabilities$42.0M$39.0M$18.0M$38.0M$60.0M
Cash$139.0M$62.0M$81.0M$215.0M$357.0M
Borrowings$4.0M$4.0M$2.0M$1.0M$0

Latest News

Praxis Precision Medicines (PRAX) Enters Into Licensing and Research Collaboration With Remagine Labs Insider Monkey · Jul 15, 2026 Goldman Sachs Initiates Praxis Precision Medicines at Buy With $447 Price Target MT Newswires · Jul 13, 2026 Praxis Precision Medicines Seen Having Greater Commercial Upside for Relutrigine, RBC Says MT Newswires · Jul 10, 2026 Praxis Precision Medicines and Remagine Labs Announce Strategic Collaboration to Develop Transdermal Ulixacaltamide for Essential Tremor GlobeNewswire · Jul 7, 2026 Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) GlobeNewswire · Jul 2, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-125.0M$-185.0M$-111.0M$-132.0M$-249.0M
Investing Cash Flow$-142.0M$96.0M$39.0M$-248.0M$-311.0M
Financing Cash Flow$3.0M$1.0M$0$2.0M$-2.0M
Net Cash Flow$-157.0M$-78.0M$20.0M$134.0M$142.0M
Free Cash Flow$-126.0M$-185.0M$-111.0M$-132.0M$-249.0M

Valuation & Return Ratios

MetricValue
PEG Ratio4.05
EV / EBITDA-22.90
FCF Yield-3.71%
Quick Ratio15.73
Interest Coverage0.00
Return 1Y421.44%
Return 3Y1135.56%
Return 5Y1.32%

Ownership

Insiders Held0.28%
Institutions Held116.76%
Institutions Float Held117.08%
Institutional HolderSharesReport Date
Janus Henderson Group PLC3,458,8632026-03-31
Orbis Allan Gray Ltd2,472,4802026-03-31
Blackrock Inc.2,324,9292026-03-31
FMR, LLC2,160,9432026-03-31
Perceptive Advisors Llc2,035,9862026-03-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
ACADACADIA Pharmaceuticals Inc. $19.78 +1.02% 8.87 $3.39B 0.00%
ADXNAddex Therapeutics Ltd $5.89 -0.17% -0.72 $4.24M 0.00%
AVXLAnavex Life Sciences Corp. $1.49 -3.25% -6.96 $138.08M 0.00%
AXSMAxsome Therapeutics, Inc. $168.35 -1.02% -49.17 $8.66B 0.00%
DNLIDenali Therapeutics Inc. $19.45 +4.18% -7.04 $3.09B 0.00%

About Praxis Precision Medicines, Inc.

Praxis Precision Medicines, Inc. is led by CEO Marcio Silva De'Souza, employs 168 people, headquartered in Boston, US, publicly traded since 2020.

Praxis Precision Medicines, Inc. (PRAX) stock trades at $259.86 with a market capitalization of $7.24B. The stock is valued at a price-to-earnings (P/E) ratio of -22.82, price-to-book of 6.42, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $50.31 and $392.70, and currently trades 33.8% below its 52-week high.

On profitability, Praxis Precision Medicines, Inc. generates a return on equity (ROE) of -34.15%, return on capital employed of -28.20%, an operating margin of 0.00%, a net profit margin of 0.00%.

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