NASDAQ · Drug Manufacturers - Specialty & Generic

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Stock

$5.33 -3.96% NASDAQ: SHPH Healthcare

Valuation

MetricValue
Price$5.33
Market Cap$3.12M
P/E Ratio-0.13
P/B Ratio0.21
P/S Ratio0.00
EPS (TTM)$-7.16
52-Week High$55.90
52-Week Low$2.58
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-156.78%
ROA-44.98%
ROCE-58.05%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.01
Current Ratio0.13

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-2.0M$-2.0M$-6.0M$-8.0M$-12.0M
Net Profit$-1.0M$-5.0M$-7.0M$-9.0M$-12.0M
EPS$-0.94$-3.00$-4.10$-8857.30$-71.60
Op Margin—————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$1.0M$9.0M$6.0M$3.0M$10.0M
Total Liabilities$2.0M$1.0M$2.0M$2.0M$8.0M
Cash$1.0M$8.0M$3.0M$2.0M$0
Borrowings$1.0M$1.0M$1.0M$1.0M$0

Latest News

Shuttle to Acquire United Dogecoin in Push to Build Public DOGE Mining Platform CryptoProwl · May 1, 2026 RETRANSMISSION: Shuttle Pharmaceuticals Launches Autonomous Self Reasoning AI Agent for Scientific Workflows TMX Newsfile · Mar 27, 2026 Shuttle Pharmaceuticals Launches Autonomous Self Reasoning AI Agent for Scientific Workflows TMX Newsfile · Mar 26, 2026 E.F. Hutton & Co. Serves as Exclusive Placement Agent on Shuttle Pharmaceuticals’ $3.5 Million Public Offering GlobeNewswire · Mar 12, 2026 Shuttle Pharmaceuticals Announces $3.5 Million Public Offering TMX Newsfile · Mar 6, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$0$-3.0M$-6.0M$-7.0M$-9.0M
Investing Cash Flow$0$0$-3.0M$3.0M$-3.0M
Financing Cash Flow$0$0$-1.0M$0$0
Net Cash Flow$0$8.0M$-6.0M$-1.0M$-2.0M
Free Cash Flow$0$-3.0M$-6.0M$-7.0M$-9.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.01
EV / EBITDA-0.28
FCF Yield-277.02%
Quick Ratio0.11
Interest Coverage-227.72
Return 1Y-92.23%
Return 3Y-99.82%
Return 5Y—

Ownership

Insiders Held0.94%
Institutions Held2.99%
Institutions Float Held3.02%
Institutional HolderSharesReport Date
Ikarian Capital, LLC68,9932025-12-31
Boothbay Fund Management, LLC20,3602025-12-31
Geode Capital Management, LLC14,4442025-12-31
UBS Group AG5,6702026-03-31
Tower Research Capital LLC (TRC)8122025-12-31

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
AAPLApple Inc. $336.64 -1.11% 38.93 $4.94T 0.32%
MSFTMicrosoft Corporation $535.07 +2.38% 28.68 $3.97T 0.76%
GOOGLAlphabet Inc. $351.66 +0.97% 16.94 $4.26T 0.26%
AMZNAmazon.com, Inc. $262.43 +3.29% 19.82 $2.82T 0.00%
METAMeta Platforms, Inc. $718.67 -0.31% 27.93 $1.83T 0.28%

About Shuttle Pharmaceuticals Holdings, Inc.

Shuttle Pharmaceuticals Holdings, Inc. is led by CEO Christopher Robert Cooper, employs 9 people, headquartered in US, publicly traded since 2022.

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) stock trades at $5.33 with a market capitalization of $3.12M. The stock is valued at a price-to-earnings (P/E) ratio of -0.13, price-to-book of 0.21, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $2.58 and $55.90, and currently trades 90.5% below its 52-week high.

On profitability, Shuttle Pharmaceuticals Holdings, Inc. generates a return on equity (ROE) of -156.78%, return on capital employed of -58.05%, an operating margin of 0.00%, a net profit margin of 0.00%.

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