NASDAQ · Biotechnology

aTyr Pharma, Inc. (ATYR) Stock

$0.17 -2.88% NASDAQ: ATYR Healthcare

Valuation

MetricValue
Price$0.17
Market Cap$16.19M
P/E Ratio-0.46
P/B Ratio0.58
P/S Ratio148.21
EPS (TTM)$-0.40
52-Week High$1.12
52-Week Low$0.16
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-95.59%
ROA-87.08%
ROCE-109.29%
Gross Margin-117.55%
Operating Margin-385.74%
Net Margin-368.57%
Debt/Equity0.23
Current Ratio5.33

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$10.0M$0$0$0
Operating Profit$-34.0M$-46.0M$-55.0M$-68.0M$-78.0M
Net Profit$-34.0M$-45.0M$-50.0M$-64.0M$-74.0M
EPS$-1.77$-1.60$-0.94$-0.86$-0.80
Op Margin—-446.8%-15557.8%-28899.6%-40856.3%

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$116.0M$96.0M$121.0M$97.0M$94.0M
Total Liabilities$6.0M$25.0M$30.0M$27.0M$27.0M
Cash$2.0M$10.0M$23.0M$11.0M$11.0M
Borrowings$1.0M$12.0M$15.0M$13.0M$12.0M

Latest News

aTyr Pharma to Present Subgroup Analysis of Phase 3 EFZO-FIT™ Study of Efzofitimod in Pulmonary Sarcoidosis at WASOG 2026 GlobeNewswire · Jul 15, 2026 What It Means To Hold Moderna Stock In A Crash Trefis · Jul 13, 2026 Life Sciences Virtual Investor Forum Presentations Now Available for On-Demand Viewing GlobeNewswire · Jun 26, 2026 Life Sciences Virtual Investor Forum Agenda Announced for June 24th & 25th GlobeNewswire · Jun 23, 2026 Atyr Pharma: Q1 Earnings Snapshot Associated Press · May 15, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-33.0M$-42.0M$-33.0M$-69.0M$-62.0M
Investing Cash Flow$-92.0M$46.0M$-24.0M$17.0M$-5.0M
Financing Cash Flow$0$0$0$0$0
Net Cash Flow$-15.0M$11.0M$13.0M$-12.0M$-1.0M
Free Cash Flow$-33.0M$-44.0M$-37.0M$-69.0M$-62.0M

Valuation & Return Ratios

MetricValue
PEG Ratio-0.02
EV / EBITDA-0.40
FCF Yield-194.67%
Quick Ratio5.12
Interest Coverage—
Return 1Y-90.31%
Return 3Y-72.03%
Return 5Y-87.88%

Ownership

Insiders Held2.45%
Institutions Held46.47%
Institutions Float Held47.64%
Institutional HolderSharesReport Date
FMR, LLC14,706,8432026-03-31
Federated Hermes, Inc.10,509,6782026-03-31
Blackrock Inc.6,443,9042026-03-31
UBS Group AG3,867,2132026-03-31
Vanguard Capital Management LLC3,812,1322026-03-31

About aTyr Pharma, Inc.

aTyr Pharma, Inc. is led by CEO Sanjay S. Shukla, employs 56 people, headquartered in US, publicly traded since 2015.

aTyr Pharma, Inc. (ATYR) stock trades at $0.17 with a market capitalization of $16.19M. The stock is valued at a negative price-to-earnings (P/E) ratio of -0.46, reflecting a net loss over the last twelve months, price-to-book of 0.58, price-to-sales of 148.21. Over the past 52 weeks the stock has ranged between $0.16 and $1.12, and currently trades 84.8% below its 52-week high.

On profitability, aTyr Pharma, Inc. generates a return on equity (ROE) of -95.59% (negative, reflecting a net loss), return on capital employed of -109.29%, an operating margin of -385.74%, a net profit margin of -368.57%.

aTyr Pharma, Inc. by the numbers, 2016–2025

Between 2016 and 2025 aTyr Pharma, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-74.0M.

The most recent net margin is -368.57%. On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-61.0M.

Borrowings rose from $10.0M to $12.0M, cash from operations was $-62.0M in the latest year, positive in 0 of the last 10.

Return on equity has averaged -70.3% over five years, and was -110.5% in the most recent year.

The share price itself has compounded at -37.6% a year over five years, -42.8% over three, -91.2% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

aTyr Pharma, Inc. (ATYR) — frequently asked questions

What is aTyr Pharma, Inc. (ATYR) stock price today?

aTyr Pharma, Inc. (ATYR) is currently trading at $0.17, down 2.88% today.

What is ATYR P/E ratio?

aTyr Pharma, Inc.'s P/E ratio is -0.46. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is ATYR return on equity (ROE)?

aTyr Pharma, Inc.'s return on equity (ROE) is -95.59%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is aTyr Pharma, Inc.'s market cap?

aTyr Pharma, Inc. has a market capitalization of $16.19M.

Does ATYR pay a dividend?

aTyr Pharma, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does ATYR carry?

aTyr Pharma, Inc. has a debt-to-equity ratio of 0.23. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is ATYR's profit margin?

aTyr Pharma, Inc. reports a net profit margin of -368.57% — the share of revenue left after every cost, including tax and interest.

What sector is ATYR in?

aTyr Pharma, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is ATYR listed on?

aTyr Pharma, Inc. trades on NASDAQ under the ticker ATYR.

What is ATYR's 52-week range?

Over the last year aTyr Pharma, Inc. has traded between $0.16 and $1.12.

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Screens ATYR currently matches

On the figures above, aTyr Pharma, Inc. passes the filters for 3 of our ready-made screens, among them Penny Stocks, Stocks Under $1, Nano Cap Stocks. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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