NMS · Biotechnology

Design Therapeutics, Inc. (DSGN) Stock

$10.24 -2.38% NMS: DSGN Healthcare

Valuation

MetricValue
Price$10.24
Market Cap$640.84M
P/E Ratio-10.46
P/B Ratio3.82
P/S Ratio0.00
EPS (TTM)$-1.22
52-Week High$17.25
52-Week Low$5.28
Dividend Yield0.00%

Financials & Margins

MetricValue
ROE-34.03%
ROA-32.91%
ROCE-38.92%
Gross Margin0.00%
Operating Margin0.00%
Net Margin0.00%
Debt/Equity0.01
Current Ratio17.23

Annual Financials (USD)

Metric20212022202320242025
Revenue$0$0$0$0$0
Operating Profit$-36.0M$-68.0M$-78.0M$-62.0M$-79.0M
Net Profit$-36.0M$-63.0M$-67.0M$-50.0M$-70.0M
EPS$-0.77$-1.14$-1.19$-0.88$-1.22
Op Margin—————

Balance Sheet (USD)

Metric20212022202320242025
Total Assets$391.0M$341.0M$290.0M$252.0M$226.0M
Total Liabilities$8.0M$14.0M$12.0M$10.0M$14.0M
Cash$299.0M$27.0M$21.0M$23.0M$17.0M
Borrowings$4.0M$4.0M$3.0M$2.0M$2.0M

Latest News

Fuchs Endothelial Corneal Dystrophy Market Forecast Highlights Significant Growth During the Forecast Period (2026-2036), Owing to the Expanding Treatment Landscape and Increasing Patient Pool | DelveInsight PR Newswire · Jul 6, 2026 Design Therapeutics Announces Initiation of Patient Dosing in Phase 1 Multiple Ascending Dose Trial of DT-818 for Myotonic Dystrophy Type-1 GlobeNewswire · Jun 30, 2026 Are Medical Stocks Lagging Atea Pharmaceuticals (AVIR) This Year? Zacks · Jun 9, 2026 Protego Biopharma Appoints Jae B. Kim, MD, as Chief Medical Officer PR Newswire · Jun 8, 2026 Design Therapeutics to Participate in 2026 Jefferies Global Healthcare Conference GlobeNewswire · May 28, 2026

Cash Flow (USD)

Metric20212022202320242025
Operating Cash Flow$-29.0M$-51.0M$-59.0M$-43.0M$-54.0M
Investing Cash Flow$-55.0M$-222.0M$52.0M$44.0M$23.0M
Financing Cash Flow$0$0$0$0$0
Net Cash Flow$296.0M$-272.0M$-5.0M$1.0M$-6.0M
Free Cash Flow$-31.0M$-52.0M$-59.0M$-43.0M$-55.0M

Valuation & Return Ratios

MetricValue
PEG Ratio1.88
EV / EBITDA-10.53
FCF Yield-7.15%
Quick Ratio18.86
Interest Coverage—
Return 1Y172.37%
Return 3Y62.66%
Return 5Y-23.55%

Peer Comparison

TickerPriceChangeP/EMarket CapDiv Yield
DYNDyne Therapeutics, Inc. $15.62 -0.95% -4.84 $2.92B 0.00%
FULCFulcrum Therapeutics, Inc. $3.68 +0.00% -3.05 $280.77M 0.00%
IONSIonis Pharmaceuticals, Inc. $42.93 -2.23% -12.57 $7.13B 0.00%
LRMRLarimar Therapeutics, Inc. $2.35 +3.52% -1.49 $244.13M 0.00%
PEPGPepGen Inc. $2.52 -6.67% -1.52 $174.31M 0.00%

About Design Therapeutics, Inc.

Design Therapeutics, Inc. is led by CEO Pratik Shah, employs 56 people, headquartered in US, publicly traded since 2021.

Design Therapeutics, Inc. (DSGN) stock trades at $10.24 with a market capitalization of $640.84M. The stock is valued at a negative price-to-earnings (P/E) ratio of -10.46, reflecting a net loss over the last twelve months, price-to-book of 3.82, price-to-sales of 0.00. Over the past 52 weeks the stock has ranged between $5.28 and $17.25, and currently trades 40.6% below its 52-week high.

On profitability, Design Therapeutics, Inc. generates a return on equity (ROE) of -34.03% (negative, reflecting a net loss), return on capital employed of -38.92%.

Design Therapeutics, Inc. by the numbers, 2019–2025

Between 2019 and 2025 Design Therapeutics, Inc. reported revenue of $0 rising to $0. Compounded, revenue has grown —% a year over five years, —% over three, —% over the last twelve months. Net profit fell to $-70.0M.

On a trailing twelve-month basis to Jun '26, revenue is $0 and net profit $-71.0M.

Borrowings rose from $1.0M to $2.0M, cash from operations was $-54.0M in the latest year, positive in 0 of the last 7.

Return on equity has averaged -21.3% over five years, and was -32.9% in the most recent year.

The share price itself has compounded at —% a year over five years, —% over three, —% over the last year. Past price movement is history, not a forecast.

Figures are as reported and in the company's own reporting currency. They describe what has already happened and carry no implication about what follows.

Design Therapeutics, Inc. (DSGN) — frequently asked questions

What is Design Therapeutics, Inc. (DSGN) stock price today?

Design Therapeutics, Inc. (DSGN) is currently trading at $10.24, down 2.38% today.

What is DSGN P/E ratio?

Design Therapeutics, Inc.'s P/E ratio is -10.46. A negative P/E means the company reported a net loss over the last twelve months, so P/E is not a meaningful valuation measure for it right now.

What is DSGN return on equity (ROE)?

Design Therapeutics, Inc.'s return on equity (ROE) is -34.03%. ROE measures net income relative to shareholders' equity. A negative ROE means the company reported a net loss over the period.

What is Design Therapeutics, Inc.'s market cap?

Design Therapeutics, Inc. has a market capitalization of $640.84M.

Does DSGN pay a dividend?

Design Therapeutics, Inc. is not currently showing a dividend yield in our data, which means no recent cash dividend was recorded for it.

How much debt does DSGN carry?

Design Therapeutics, Inc. has a debt-to-equity ratio of 0.01. That compares total borrowings with shareholders' equity: a figure under 1 means equity exceeds debt.

What is DSGN's profit margin?

Design Therapeutics, Inc. reports a net profit margin of 0.00% — the share of revenue left after every cost, including tax and interest.

What sector is DSGN in?

Design Therapeutics, Inc. is classified under Healthcare, in the Biotechnology industry. Ratios are most informative compared with other companies in the same industry rather than across the whole market.

Which exchange is DSGN listed on?

Design Therapeutics, Inc. trades on NMS under the ticker DSGN.

What is DSGN's 52-week range?

Over the last year Design Therapeutics, Inc. has traded between $5.28 and $17.25.

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Screens DSGN currently matches

On the figures above, Design Therapeutics, Inc. passes the filters for 7 of our ready-made screens, among them Small Cap Stocks, Debt Free Stocks Under $100, Debt Free Stocks. Appearing on a screen means the numbers meet its filters today and nothing more; the list is rebuilt whenever the data changes.

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Data for information only, not investment advice. Figures may be delayed or inaccurate; verify against company filings. See our disclaimer.